IDF2022-0661 2-h Postprandial Blood Glucose Lower Than Fasting Blood Glucose in China: a cross-sectional study

Usually blood glucose levels measured in the fasted status (fasting glucose) are lower than fed (postprandial glucose). However, postprandial (PBG) fasting (FBG) can be found some cases. This study aims to describe prevalence, clinical characteristics, and contributing risk factors for PBG ≤F BG. It’s a nationwide cohort [the National Key R&D Program of China (2016YFC1305700)] conducted China, 16,116 people had an oral tolerance test, haematology, biochemistry tests, sociodemographic anthropometric data collection. We calculated prevalence BG (‘Low Post Load’ group) PBG>FBG (‘High group), used logistic regression evaluate association with factors. A total natural population [mean age: 49.95 ± 11.82 years old; 10,635 females (65.99%); mean BMI: 25.07 3.86 kg/m2] were included. The was 24.13% group, n = 3,889) 75.87% 12,227). Compared participants High Load Low group FBG (5.53 0.88 vs 5.70 1.28, P < 0.000), (4.64 0.91 8.03 3.13, 0.000) HbA1c (5.33 0.52 5.55 0.83, 0.000). People ≤FBG more likely have hypoglycaemia incidence impaired (IFG, FBG: 6.1–6.9 mmol/L) compared (P (Fig. 1). In analyses associated age<44 years; male; Uyghur or Zhuang ethnicity; BMI<24 kg/m2; normal pressure; heart rate<100 beats/min; as never drinker former drinker; HDL cholesterol≥1.55 mmol/L; TG<1.70 mmol/L, all 0.000. is related young age, BMI, pressure, higher cholesterol TG. IFG PBG>FBG. relationship between this phenomenon progression diabetes needs further exploration longitudinal analyses.